Sugar substitutes have become a significant part of the modern American diet. For those seeking to reduce calorie intake or manage conditions like diabetes, low-calorie sweeteners often seem like a healthier alternative to sugar. However, as these sugar substitutes grow in popularity, questions about their long-term health effects continue to arise. One emerging concern is whether these artificial sweeteners might increase the risk of blood clots and related vascular issues.
In this blog, we'll dive into recent research on the link between sugar substitutes and blood clotting and what you should know to protect your vein health.
The search for healthier alternatives to sugar is nothing new. Over the years, a wave of sugar substitutes has hit the market, from aspartame and saccharin to stevia and erythritol. These alternatives promise the sweetness of sugar without the added calories, making them particularly appealing for those watching their weight or managing conditions such as diabetes.
Among these options, erythritol, a type of sugar alcohol, has gained popularity due to its low-calorie content, minimal impact on blood sugar levels, and generally favorable taste. Erythritol is found in "natural" sugar-free sweeteners and many low-calorie or keto-friendly products.
Recent research has raised concerns about this seemingly innocent sweetener. A study published by the National Institutes of Health (NIH) in 2023 has suggested that erythritol could potentially increase the risk of blood clotting, which, in turn, may lead to cardiovascular events like heart attacks and strokes.
According to a new pilot study reported by CNN, consuming one drink with erythritol more than doubled the risk of blood clotting in healthy people.
Per an August 2024 study reported by the Cleveland Clinic, "ingesting the non-nutritive sweetener erythritol — at a dose typically contained in a "sugarless" soda or muffin — rapidly enhances platelet reactivity in human blood and thereby increases thrombosis potential."
Erythritol appears to make blood platelets more likely to stick together, which is a key step in clot formation. While clots are a natural part of the body's healing process when you have an injury, they can block blood vessels when they form unnecessarily. If a clot forms in the veins (a condition known as deep vein thrombosis or DVT), it can travel to the lungs and cause a life-threatening pulmonary embolism. In arteries, clots can block blood flow to the heart or brain, leading to heart attacks or strokes.
While the study's findings are concerning, it's important to put the data into context. First, the study highlights an association between erythritol and blood clot risk—it does not necessarily prove that erythritol causes these events. There could be other underlying factors at play. For instance, individuals with higher erythritol levels in the study were already at a greater risk of cardiovascular issues, which may have influenced the results.
Another point to consider is the quantity of erythritol that may pose a risk. Erythritol naturally occurs in small amounts in fruits and vegetables, but the levels examined in the study were far higher, reflecting the amounts found in processed foods or supplements containing erythritol.
Still, these findings emphasize the importance of being aware of what's in your food and how it might affect your health—especially cardiovascular and venous health.
Veins play a crucial role in returning blood to the heart. When the veins become damaged or blood flow becomes sluggish, conditions like deep vein thrombosis (DVT), chronic venous insufficiency, and varicose veins can develop.
The possibility that certain sugar substitutes might increase your risk of blood clots is something that should be taken seriously, especially if you already have other risk factors for vein problems, such as:
If you fall into any of these categories, it's especially important to consider how even small dietary changes might influence your vein health.
Center for Vein Restoration (CVR) is a leading national provider of vein care, offering minimally invasive treatments for conditions like varicose veins, spider veins, venous ulcers, and more. CVR's board-certified vein specialists deliver personalized care in comfortable outpatient settings, utilizing advanced techniques that allow for fast recovery and a quick return to healthy, comfortable legs.
Call 240-965-3915 to speak to a Patient Services Representative or schedule your consultation online at a CVR near you today.
While it's too early to make definitive recommendations, it's wise to be cautious. If you regularly consume foods containing erythritol, you may want to monitor your intake, especially if you have existing cardiovascular or venous health issues. This doesn't mean you have to eliminate it from your diet, but moderation is key.
It's also a good idea to consult with your healthcare provider if you're concerned about how sugar substitutes might impact your venous health. Your provider can assess your individual risk factors and offer personalized guidance.
Whether or not you use sugar substitutes, there are steps you can take to support your vein health and reduce your overall risk of blood clots:
Stay active: Regular physical activity improves circulation and helps prevent blood from pooling in the veins.
Maintain a healthy weight: Managing your weight reduces pressure on your veins and lowers your risk of clots.
Stay hydrated: Proper hydration keeps blood flowing smoothly, making it less likely to clot.
Wear compression stockings: The gentle hug of compression stockings improves blood flow, thus reducing swelling and pain. In addition, compression stockings stop blood from pooling and clotting; therefore, they are recommended for DVT prevention.
If you have concerns about your venous health, don't hesitate to contact a Center for Vein Restoration vein specialist who can provide expert advice tailored to your specific needs.
Your veins deserve care and attention—they're vital to your overall health and well-being!
The link between erythritol and increased blood clot risk is still being explored, but it's a development worth paying attention to, especially for those predisposed to venous conditions.
The takeaway? Like with many things in life, moderation is key. Stay informed, be mindful of your consumption, and take proactive steps to keep your veins healthy.
Concerned that you might be experiencing a DVT? Center for Vein Restoration (CVR) offers a same-day DVT-rule-out service. If needed, CVR can provide anticoagulation treatment, education, and follow-up. Our hotline is 877-SCAN-DVT (866-969-3470).
Center for Vein Restoration (CVR) is a nationally recognized leader in treating varicose and spider veins. They offer a variety of nearly pain-free solutions to eliminate unsightly and uncomfortable veins. CVR provides state-of-the-art vascular care compassionately and affordably, aiming to continuously redefine the care of patients with venous disorders by providing comprehensive vein care throughout the United States.
Call 240-965-3915 to speak to a Patient Services Representative or schedule your consultation online at a CVR near you today.