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Understanding the Connection Between Vein Disease and Lymphedema

Written By Center for Vein Restoration
Blog Image Understanding the Connection Between Vein Disease and Lymphedema 1
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Vein disease and lymphedema are two distinct health conditions affecting millions worldwide. Brigham and Women’s Hospital estimates that 50 percent of all Americans are believed to have some venous (vein) or lymphatic disorder. Although they are separate issues, vein disease, and lymphedema often share symptoms and can even appear together, making diagnosis and treatment challenging.

Limb swelling, also known as edema, is a complex condition in which excess fluid becomes trapped in body tissues, especially in the arms, hands, ankles, legs, and feet. This swelling can be caused by temporary causes like fluid retention or more serious conditions, such as chronic venous insufficiency or lymphedema, requiring specialized treatment to manage effectively.

Chronic venous insufficiency (CVI) is a progressive disorder in which weakened or damaged vein valves prevent blood from flowing effectively back to the heart, causing blood to pool in the legs. This pooling increases pressure within the veins, often leading to symptoms such as swelling, leg pain, and the development of varicose or spider veins.

Understanding the differences and similarities between these conditions can empower you to recognize symptoms early and seek the right treatment near you.

Understanding Chronic Venous Insufficiency (CVI)

Chronic venous insufficiency, also known as vein disease, is a circulatory condition that affects the veins in the legs. Healthy veins contain one-way valves that help keep blood flowing back toward the heart. However, in CVI, these valves become damaged, allowing blood to pool in the lower legs. This blood pooling creates pressure in the veins, resulting in varicose veins, spider veins, leg pain, and swelling.

CVI is most common in people over 50, as age weakens vein valves, making it harder for them to pump blood efficiently. Other factors that increase CVI risk include prolonged sitting or standing, family history, obesity, and vein trauma or blood clots.

Unlike lymphedema, swelling from CVI is typically symmetrical, meaning it appears in both lower legs or ankles. The swelling tends to get worse during the day, particularly after standing or sitting for extended periods and often decreases overnight when the legs are elevated.

Understanding Lymphedema

Lymphedema is a chronic condition characterized by swelling in the limbs due to a buildup of lymph fluid. The lymphatic system, responsible for fluid balance and immune function, circulates lymph fluid throughout the body. However, if this fluid becomes trapped in the tissue due to blockage or damage, it results in swelling. Lymphedema typically affects the arms or legs and can develop in two forms:

  • Primary Lymphedema: This type is hereditary, caused by a malfunctioning lymphatic system present from birth or developing over time.
  • Secondary Lymphedema: This form is more common and results from trauma or damage to the lymphatic system, such as surgery, radiation, cancer treatments, or infections.

Lymphedema-related swelling often affects the entire arm or leg and may be asymmetrical, meaning it usually affects only one side of the body. Significantly, this type of swelling does not typically reduce overnight, although some improvement may be seen in the condition’s early stages.

Lymphedema vs. Chronic Venous Insufficiency: Understanding the Differences

Although both lymphedema and CVI cause swelling, they have distinct characteristics, making it essential to understand each condition’s unique symptoms and how they affect the body differently.

  1. Cause and Onset of Swelling:
    • Lymphedema results from blockages or damage in the lymphatic system, leading to tissue fluid buildup. This can happen at any age, particularly in cases of primary lymphedema. Secondary lymphedema often develops later in life due to trauma, infection, or cancer treatments.
    • CVI, however, occurs primarily due to weakened or damaged vein valves in the legs, which are more common in people over 50. The condition develops gradually and may worsen over time without treatment.
  2. Appearance and Timing of Swelling:
    • Lymphedema-related swelling is often asymmetrical, affecting one side of the body and typically involving the entire limb, such as the whole leg or arm. Unlike CVI, lymphedema swelling doesn’t usually improve overnight unless the condition is in its very early stages.
    • CVI swelling is generally symmetrical, affecting both lower legs or ankles. This type of swelling often worsens throughout the day and lessens overnight when the legs are elevated.
  3. Pain and Discomfort:
    • Pain levels vary between the two conditions. Lymphedema doesn’t usually cause pain with walking or standing, though swelling can lead to discomfort, heaviness, and joint stiffness.
    • By contrast, CVI can cause aching or throbbing pain, which intensifies after standing or walking and typically improves with leg elevation.

These differences in symptoms are important indicators, and a visit to a vein doctor or vein center can help you get an accurate diagnosis and a tailored treatment plan.

Treatment for Lymphedema and Vein Disease

While neither lymphedema nor CVI can be fully cured, treatments are available to manage symptoms, reduce swelling, and improve quality of life.

Managing Vein Disease
For CVI, treatments aim to restore blood flow, reduce swelling, and alleviate pain. Treatment options include:

  • Compression Stockings: These stockings help support vein health and reduce daily swelling.
  • Minimally Invasive Procedures: For advanced CVI, vein specialists may recommend procedures such as:
    • Vein Ablation: Uses heat or laser energy to close damaged veins.
    • Sclerotherapy: Involves injecting a solution into varicose veins, causing them to collapse and shrink.
    • Microphlebectomy or Ambulatory Phlebectomy: An office-based procedure to remove problematic veins through small incisions that require only a band-aid afterward.

If you’re struggling with persistent leg pain, swelling, or visible veins, the experts at Center for Vein Restoration are here to help. Our team of specialized vein doctors is dedicated to treating venous conditions like chronic venous insufficiency and varicose veins, providing comprehensive diagnostics and personalized treatment options.

Take our self-assessment HERE to learn if you are at risk of vein disease.

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Managing Lymphedema
For lymphedema, treatment focuses on moving lymph fluid and reducing swelling. One effective approach is complex decongestive therapy (CDT), which combines several therapies to reduce limb volume and maintain function:

  • Compression Therapy: Special wraps or compression garments can help keep lymph fluid from accumulating.
  • Manual Lymphatic Drainage (MLD): A specialized massage technique that helps drain lymph fluid.
  • Exercise: Carefully guided movement helps support lymphatic flow.
  • Skin Care: Proper skin care helps reduce infection risk in affected areas.

In cases of severe lymphedema, a lymphedema specialist may recommend further intervention, including surgical options to aid fluid drainage.

Each of these treatments has a unique role in addressing CVI symptoms, and a consultation with a vein expert can help determine the most suitable approach for you.

What Happens if Vein Disease with Lymphedema is Not Treated?

A study by the National Library of Medicine (NIH) explores phlebolymphedema, a commonly underdiagnosed condition in wound care resulting from chronic venous insufficiency (CVI) and lymphatic dysfunction.

The term merges "phlebology" (the study of venous disease) and "lymphedema" (a lymphatic disorder that causes abnormal swelling). Phlebolymphedema often results from chronic venous insufficiency, where venous hypertension overwhelms the lymphatic system’s capacity, allowing protein-rich fluid to accumulate in tissues. Compounding factors like heart failure, obesity, and infections increase the likelihood of this condition, which can lead to severe complications, including skin changes and infections if untreated.

This study highlights the importance of diagnosing and treating phlebolymphedema early, as prompt management can mitigate complications and improve patient quality of life.

Preventing Varicose Veins and Supporting Vein Health

Taking preventive measures can help reduce the risk of varicose veins and chronic venous insufficiency. Lifestyle habits such as regular exercise, maintaining a healthy weight, avoiding prolonged standing or sitting, and wearing compression stockings if needed can all support vein health. However, you must consult a board-certified vein doctor if you’re already experiencing symptoms such as leg pain, visible veins, or swelling. Early treatment can help manage symptoms and prevent further complications.

At Center for Vein Restoration, our highly trained vein care team combines years of expertise with state-of-the-art technology to create personalized treatment plans for each patient. We’re committed to helping you find the relief you’re looking for. Call 240-965-3915 to speak to a Patient Services Representative or schedule your consultation online at a CVR near you today.

When to Seek Help for Problem Veins

Living with lymphedema or chronic venous insufficiency can affect your comfort and quality of life, but timely treatment can make a big difference. If you’re experiencing persistent swelling, leg pain, or changes in your skin, consider seeing a vein specialist.

Don’t let vein disease or lymphedema affect your daily comfort and mobility. Center for Vein Restoration is here to support you with expert care tailored to your unique needs. Our experienced vein specialists provide a full range of services, from diagnostic assessments to innovative treatments designed to alleviate symptoms and improve circulation. With our compassionate, patient-centered approach, you can trust that your vein health is in the best hands.

Contact us at 240-965-3915 or schedule your consultation online.

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