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Restless Leg Syndrome: What Triggers Flare-Ups?

Written By Center for Vein Restoration
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Restless legs can be more than just an annoying sensation. They can significantly disrupt your quality of life, making it hard to relax, fall asleep, or even sit through a long car ride. If you’ve ever found yourself constantly moving your legs to get comfortable or feeling a nagging urge to stretch them, especially at night, you might be experiencing restless leg syndrome (RLS).

Don’t let restless legs keep you up at night or hold you back during the day. Take the first step toward relief—schedule a consultation with a vein specialist at Center for Vein Restoration (CVR). With over 110 locations nationwide, our board-certified vein doctors can help you uncover the root cause of your symptoms and find practical, personalized solutions.

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Reclaim your comfort and enjoy better sleep (and a better quality of life!)

In this blog, we’ll uncover the hidden causes of restless leg flare-ups and share practical tips for finding lasting relief.

What is Restless Leg Syndrome?

Restless leg syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by uncomfortable sensations in the legs and an irresistible urge to move them. According to the National Institute of Neurological Disorders and Stroke (NIH), these urges typically worsen in the late afternoon or evening, severely disrupting sleep, leading to exhaustion, daytime sleepiness, mood changes, difficulty concentrating, memory problems, and even depression or anxiety.

While some people experience mild symptoms only once or twice a week, those with more severe RLS may struggle with nightly symptoms that significantly impact their quality of life and daily functioning.

Common Symptoms of Restless Leg Syndrome:

  • An uncontrollable urge to move the legs, often accompanied by uncomfortable sensations like tingling, burning, or aching
  • Symptoms that get worse in the evening or at night
  • Temporary relief with movement, like walking or stretching
  • Difficulty falling or staying asleep due to leg discomfort
  • Daytime fatigue or sleepiness due to disrupted sleep

While RLS can occur on its own, it is sometimes linked to underlying medical conditions, including vein problems like varicose veins and chronic venous insufficiency (CVI).

Say Goodbye to Restless Legs

Don’t let vein problems keep you up at night. Center for Vein Restoration’s board-certified vein specialists offer advanced treatments that address the root cause of restless legs, helping you find lasting relief. Schedule your consultation today and take the first step toward healthier, more comfortable legs.

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Why is Restless Leg Syndrome Worse at Night?

According to the Cleveland Clinic, RLS symptoms often worsen at night due to natural variations in dopamine levels. Dopamine, a brain chemical that helps control muscle movement, follows a daily cycle, with levels typically peaking in the morning and gradually declining throughout the day. This decrease in dopamine in the evening can lead to more pronounced muscle twitching, involuntary movements, and uncomfortable sensations characteristic of RLS.

Additionally, lying down or resting for extended periods, which is more common at night, can further aggravate RLS symptoms by reducing overall circulation and increasing pressure in the legs.

Can Vein Problems Cause Restless Legs?

Yes, vein problems can be a significant contributor to restless leg symptoms. Chronic venous insufficiency, a condition where the veins in the legs struggle to return blood to the heart, can cause leg swelling, heaviness, and restlessness.

The Cleveland Clinic states that when vein valves become weakened or damaged, blood pools in the legs, increasing pressure in the veins and causing uncomfortable sensations that can mimic RLS.

A study presented at the American Venous Forum in 2020 reported that 78 percent of patients with superficial venous insufficiency also experienced RLS symptoms, compared to 44 percent without venous disease. This suggests a 34.5 percent higher prevalence of RLS in patients with venous reflux.

Signs that your restless legs may be vein-related include:

  • Swollen, heavy, or aching legs

Legs that feel full or heavy

  • Burning, tingling, or a “pins and needles” sensation in the legs
  • Visible varicose veins
  • Symptoms that worsen after prolonged sitting or standing
  • Relief with leg elevation or compression stockings

Why Vein Problems Can Trigger Restless Legs

Poor circulation is linked to vein disease and restless legs. When blood pools in the lower legs, it increases pressure in the veins, causing inflammation and discomfort. This can lead to the “creepy-crawly” or “itchy” sensations often associated with restless legs.

Treating the underlying vein disease can often reduce or eliminate RLS symptoms, providing lasting relief.

According to a study published by the National Library of Medicine (NIH), patients who underwent ultrasound-guided foam sclerotherapy (USGFS) for LSVP insufficiency experienced significant relief from RLS symptoms, with 93 percent maintaining improvement at one-year follow-up.

Find Lasting Relief from Restless Legs
Center for Vein Restoration (CVR) is the trusted choice for diagnosing and treating vein disease, including conditions that may contribute to restless legs. Schedule a consultation with a board-certified vein specialist today to get to the root of your symptoms and experience real, lasting relief.

📞 Call CVR at 240-965-3915
📅 Or book online HERE

Other Common Causes of Restless Legs

While vein disease is a common cause, other factors can also contribute to restless leg syndrome, including:

  • Iron deficiency or anemia
  • Nerve damage or peripheral neuropathy
  • Kidney disease
  • Pregnancy (due to increased blood volume and pressure on leg veins)
  • Certain medications, including antidepressants or antihistamines
  • Lifestyle factors like caffeine or alcohol use
  • Family history of RLS

How to Prevent Restless Legs from Flaring Up

If you experience restless legs, there are steps you can take to reduce flare-ups and improve your overall vein health:

  1. Stay Active – Regular exercise improves circulation and reduces leg discomfort.
  2. Wear Compression Stockings – These can help reduce leg swelling and improve blood flow.
  3. Elevate Your Legs – Raising your legs above heart level can help reduce pressure in the veins.
  4. Avoid Triggers – Limit caffeine, alcohol, and smoking, which can worsen RLS symptoms.
  5. Maintain a Healthy Weight – Reducing excess weight can reduce pressure on your veins and lower the risk of vein disease.
  6. Stay Hydrated – Proper hydration can support healthy circulation.

When to See a Vein Specialist

If your restless legs are becoming more frequent or severe, or if you have other signs of vein disease like leg swelling, heaviness, or visible varicose veins, it’s time to see a vein expert. A vein doctor can evaluate your symptoms, check for signs of chronic venous insufficiency, and recommend personalized, minimally invasive vein treatments to provide lasting relief.

At Center for Vein Restoration, our board-certified vein specialists use advanced diagnostic tools, such as duplex ultrasound, to assess your vein health and identify the root cause of your symptoms.

Minimally invasive vein treatment options may include:

  • Sclerotherapy – A simple injection to close off small, damaged veins.
  • Endovenous Laser Therapy (EVLT) – Uses laser energy to seal off large varicose veins.
  • Radiofrequency Ablation (RFA) – Similar to EVLT but uses heat energy to close off diseased veins.
  • Varithena – An FDA-approved microfoam therapy to collapse large varicose veins.

Take the First Step Toward Restful Legs

If restless legs keep you up at night or affect your quality of life, don’t wait! Schedule a consultation with a vein specialist at Center for Vein Restoration. With over 110 locations nationwide, our team of vein experts is dedicated to helping you find relief from vein-related restless leg symptoms and improving your overall vein health.

Call 240-965-3915 or BOOK ONLINE TODAY to take the first step toward healthier, more comfortable legs.

Frequently Asked Questions

  1. What is restless leg syndrome (RLS), and what causes it?
    Restless leg syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs, often accompanied by uncomfortable sensations like tingling, burning, or aching. It typically worsens at night and can disrupt sleep, leading to daytime fatigue, mood changes, and difficulty concentrating. Common triggers include vein disease, iron deficiency, and nerve damage.
  2. Can vein problems cause restless leg symptoms?
    Yes, chronic venous insufficiency (CVI) and varicose veins are common contributors to restless leg symptoms. When vein valves are weakened or damaged, blood can pool in the lower legs, increasing pressure in the veins and causing uncomfortable sensations that mimic RLS.
  3. Why do restless leg symptoms get worse at night?
    According to the Cleveland Clinic, RLS symptoms often worsen at night due to natural variations in dopamine levels. Dopamine, a brain chemical that helps control muscle movement, decreases in the evening, which can lead to more pronounced muscle twitching, involuntary movements, and discomfort.
  4. How can I prevent restless leg flare-ups?
    You can reduce restless leg flare-ups by staying active, wearing compression stockings, elevating your legs, avoiding known triggers like caffeine or alcohol, and maintaining a healthy weight. For persistent or severe symptoms, a consultation with a Center for Vein Restoration vein specialist can help to diagnose and address underlying vein issues.
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